Feasibility study for the use of self-collected nasal swabs to identify pathogens among participants of a population-based surveillance system for acute respiratory infections (GrippeWeb-Plus)-Germany, 2016.
Identifieur interne : 000015 ( Main/Exploration ); précédent : 000014; suivant : 000016Feasibility study for the use of self-collected nasal swabs to identify pathogens among participants of a population-based surveillance system for acute respiratory infections (GrippeWeb-Plus)-Germany, 2016.
Auteurs : Joana M. Haussig [Allemagne, Suède] ; Angelina Targosz [Allemagne] ; Susanne Engelhart [Allemagne] ; Michael Herzhoff [Allemagne] ; Kerstin Prahm [Allemagne] ; Silke Buda [Allemagne] ; Andreas Nitsche [Allemagne] ; Walter Haas [Allemagne] ; Udo Buchholz [Allemagne]Source :
- Influenza and other respiratory viruses [ 1750-2659 ] ; 2019.
Descripteurs français
- KwdFr :
- Adulte, Allemagne, Enfant, Enquêtes et questionnaires, Grippe humaine (diagnostic), Humains, Infections de l'appareil respiratoire (diagnostic), Infections de l'appareil respiratoire (virologie), Maladie aigüe (épidémiologie), Nez (virologie), Prélèvement biologique (), Prélèvement biologique (normes), Virus (génétique), Virus (isolement et purification), Épidémiosurveillance, Études de faisabilité.
- MESH :
- diagnostic : Grippe humaine, Infections de l'appareil respiratoire.
- génétique : Virus.
- isolement et purification : Virus.
- normes : Prélèvement biologique.
- virologie : Infections de l'appareil respiratoire, Nez.
- épidémiologie : Maladie aigüe.
- Adulte, Allemagne, Enfant, Enquêtes et questionnaires, Humains, Prélèvement biologique, Épidémiosurveillance, Études de faisabilité.
- Wicri :
- geographic : Allemagne.
English descriptors
- KwdEn :
- Acute Disease (epidemiology), Adult, Child, Epidemiological Monitoring, Feasibility Studies, Germany, Humans, Influenza, Human (diagnosis), Nose (virology), Respiratory Tract Infections (diagnosis), Respiratory Tract Infections (virology), Specimen Handling (methods), Specimen Handling (standards), Surveys and Questionnaires, Viruses (genetics), Viruses (isolation & purification).
- MESH :
- geographic : Germany.
- diagnosis : Influenza, Human, Respiratory Tract Infections.
- epidemiology : Acute Disease.
- genetics : Viruses.
- isolation & purification : Viruses.
- methods : Specimen Handling.
- standards : Specimen Handling.
- virology : Nose, Respiratory Tract Infections.
- Adult, Child, Epidemiological Monitoring, Feasibility Studies, Humans, Surveys and Questionnaires.
Abstract
BACKGROUND
Internet-based participatory surveillance systems, such as the German GrippeWeb, monitor the frequency of acute respiratory illnesses on population level. In order to interpret syndromic information better, we devised a microbiological feasibility study (GrippeWeb-Plus) to test whether self-collection of anterior nasal swabs is operationally possible, acceptable for participants and can yield valid data.
METHODS
We recruited 103 GrippeWeb participants (73 adults and 30 children) and provided them with a kit, instructions and a questionnaire for each sample. In the first half of 2016, participants took an anterior nasal swab and sent it to the Robert Koch Institute whenever an acute respiratory illness occurred. Reporting of illnesses through the GrippeWeb platform continued as usual. We analysed swabs for the presence of human c-myc-DNA and 22 viral and bacterial pathogens. After the study, we sent participants an evaluation questionnaire. We analysed timeliness, completeness, acceptability and validity.
RESULTS
One hundred and two participants submitted 225 analysable swabs. Ninety per cent of swabs were taken within 3 days of symptom onset. Eighty-nine per cent of swabs had a corresponding reported illness in the GrippeWeb system. Ninety-nine per cent of adults and 96% of children would be willing to participate in a self-swabbing scheme for a longer period. All swabs contained c-myc-DNA. In 119 swabs, we identified any of 14 viruses but no bacteria. The positivity rate of influenza was similar to that in the German physician sentinel.
CONCLUSION
Self-collection of anterior nasal swabs proofed to be feasible, was well accepted by participants, gave valid results and was an informative adjunct to syndromic data.
DOI: 10.1111/irv.12644
PubMed: 30925029
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
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first="Joana M" last="Haussig">Joana M. Haussig</name><affiliation wicri:level="3"><nlm:affiliation>Department of Infectious Disease Epidemiology, Robert Koch Institute, Berlin, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Infectious Disease Epidemiology, Robert Koch Institute, Berlin</wicri:regionArea><placeName><region type="land" nuts="3">Berlin</region><settlement type="city">Berlin</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:affiliation>Postgraduate Training for Applied Epidemiology (PAE), Robert Koch Institute, Berlin, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Postgraduate Training for Applied Epidemiology (PAE), Robert Koch Institute, Berlin</wicri:regionArea><placeName><region type="land" nuts="3">Berlin</region><settlement type="city">Berlin</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:affiliation>European Centre for Disease Prevention and Control (ECDC), 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first="Susanne" last="Engelhart">Susanne Engelhart</name><affiliation wicri:level="3"><nlm:affiliation>Centre for Biological Threats and Special Pathogens, Robert Koch Institute, Berlin, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Centre for Biological Threats and Special Pathogens, Robert Koch Institute, Berlin</wicri:regionArea><placeName><region type="land" nuts="3">Berlin</region><settlement type="city">Berlin</settlement></placeName></affiliation></author><author><name sortKey="Herzhoff, Michael" sort="Herzhoff, Michael" uniqKey="Herzhoff M" first="Michael" last="Herzhoff">Michael Herzhoff</name><affiliation wicri:level="3"><nlm:affiliation>Department of Infectious Disease Epidemiology, Robert Koch Institute, Berlin, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Infectious Disease Epidemiology, Robert Koch Institute, Berlin</wicri:regionArea><placeName><region type="land" nuts="3">Berlin</region><settlement type="city">Berlin</settlement></placeName></affiliation></author><author><name sortKey="Prahm, Kerstin" sort="Prahm, Kerstin" uniqKey="Prahm K" first="Kerstin" last="Prahm">Kerstin Prahm</name><affiliation wicri:level="3"><nlm:affiliation>Department of Infectious Disease Epidemiology, Robert Koch Institute, Berlin, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Infectious Disease Epidemiology, Robert Koch Institute, Berlin</wicri:regionArea><placeName><region type="land" nuts="3">Berlin</region><settlement type="city">Berlin</settlement></placeName></affiliation></author><author><name sortKey="Buda, Silke" sort="Buda, Silke" uniqKey="Buda S" first="Silke" last="Buda">Silke Buda</name><affiliation wicri:level="3"><nlm:affiliation>Department of Infectious Disease Epidemiology, Robert Koch Institute, Berlin, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Infectious Disease Epidemiology, Robert Koch Institute, Berlin</wicri:regionArea><placeName><region type="land" nuts="3">Berlin</region><settlement type="city">Berlin</settlement></placeName></affiliation></author><author><name sortKey="Nitsche, Andreas" sort="Nitsche, Andreas" uniqKey="Nitsche A" first="Andreas" last="Nitsche">Andreas Nitsche</name><affiliation wicri:level="3"><nlm:affiliation>Centre for Biological Threats and Special Pathogens, Robert Koch Institute, Berlin, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Centre for Biological Threats and Special Pathogens, Robert Koch Institute, Berlin</wicri:regionArea><placeName><region type="land" nuts="3">Berlin</region><settlement type="city">Berlin</settlement></placeName></affiliation></author><author><name sortKey="Haas, Walter" sort="Haas, Walter" uniqKey="Haas W" first="Walter" last="Haas">Walter Haas</name><affiliation wicri:level="3"><nlm:affiliation>Department of Infectious Disease Epidemiology, Robert Koch Institute, Berlin, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Infectious Disease Epidemiology, Robert Koch Institute, Berlin</wicri:regionArea><placeName><region type="land" nuts="3">Berlin</region><settlement type="city">Berlin</settlement></placeName></affiliation></author><author><name sortKey="Buchholz, Udo" sort="Buchholz, Udo" uniqKey="Buchholz U" first="Udo" last="Buchholz">Udo Buchholz</name><affiliation wicri:level="3"><nlm:affiliation>Department of Infectious Disease Epidemiology, Robert Koch Institute, Berlin, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Infectious Disease Epidemiology, Robert Koch Institute, Berlin</wicri:regionArea><placeName><region type="land" nuts="3">Berlin</region><settlement type="city">Berlin</settlement></placeName></affiliation></author></analytic><series><title level="j">Influenza and other respiratory viruses</title><idno type="eISSN">1750-2659</idno><imprint><date when="2019" type="published">2019</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Acute Disease (epidemiology)</term><term>Adult</term><term>Child</term><term>Epidemiological Monitoring</term><term>Feasibility Studies</term><term>Germany</term><term>Humans</term><term>Influenza, Human (diagnosis)</term><term>Nose (virology)</term><term>Respiratory Tract Infections (diagnosis)</term><term>Respiratory Tract Infections (virology)</term><term>Specimen Handling (methods)</term><term>Specimen Handling (standards)</term><term>Surveys and Questionnaires</term><term>Viruses (genetics)</term><term>Viruses (isolation & purification)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adulte</term><term>Allemagne</term><term>Enfant</term><term>Enquêtes et questionnaires</term><term>Grippe humaine (diagnostic)</term><term>Humains</term><term>Infections de l'appareil respiratoire (diagnostic)</term><term>Infections de l'appareil respiratoire (virologie)</term><term>Maladie aigüe (épidémiologie)</term><term>Nez (virologie)</term><term>Prélèvement biologique ()</term><term>Prélèvement biologique (normes)</term><term>Virus (génétique)</term><term>Virus (isolement et purification)</term><term>Épidémiosurveillance</term><term>Études de faisabilité</term></keywords><keywords scheme="MESH" type="geographic" xml:lang="en"><term>Germany</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Influenza, Human</term><term>Respiratory Tract Infections</term></keywords><keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr"><term>Grippe humaine</term><term>Infections de l'appareil respiratoire</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Acute Disease</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Viruses</term></keywords><keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Virus</term></keywords><keywords scheme="MESH" qualifier="isolation & purification" xml:lang="en"><term>Viruses</term></keywords><keywords scheme="MESH" qualifier="isolement et purification" xml:lang="fr"><term>Virus</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Specimen Handling</term></keywords><keywords scheme="MESH" qualifier="normes" xml:lang="fr"><term>Prélèvement biologique</term></keywords><keywords scheme="MESH" qualifier="standards" xml:lang="en"><term>Specimen Handling</term></keywords><keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Infections de l'appareil respiratoire</term><term>Nez</term></keywords><keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Nose</term><term>Respiratory Tract Infections</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Maladie aigüe</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Child</term><term>Epidemiological Monitoring</term><term>Feasibility Studies</term><term>Humans</term><term>Surveys and Questionnaires</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adulte</term><term>Allemagne</term><term>Enfant</term><term>Enquêtes et questionnaires</term><term>Humains</term><term>Prélèvement biologique</term><term>Épidémiosurveillance</term><term>Études de faisabilité</term></keywords><keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>Allemagne</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p><b>BACKGROUND</b></p><p>Internet-based participatory surveillance systems, such as the German GrippeWeb, monitor the frequency of acute respiratory illnesses on population level. In order to interpret syndromic information better, we devised a microbiological feasibility study (GrippeWeb-Plus) to test whether self-collection of anterior nasal swabs is operationally possible, acceptable for participants and can yield valid data.</p></div><div type="abstract" xml:lang="en"><p><b>METHODS</b></p><p>We recruited 103 GrippeWeb participants (73 adults and 30 children) and provided them with a kit, instructions and a questionnaire for each sample. In the first half of 2016, participants took an anterior nasal swab and sent it to the Robert Koch Institute whenever an acute respiratory illness occurred. Reporting of illnesses through the GrippeWeb platform continued as usual. We analysed swabs for the presence of human c-myc-DNA and 22 viral and bacterial pathogens. After the study, we sent participants an evaluation questionnaire. We analysed timeliness, completeness, acceptability and validity.</p></div><div type="abstract" xml:lang="en"><p><b>RESULTS</b></p><p>One hundred and two participants submitted 225 analysable swabs. Ninety per cent of swabs were taken within 3 days of symptom onset. Eighty-nine per cent of swabs had a corresponding reported illness in the GrippeWeb system. Ninety-nine per cent of adults and 96% of children would be willing to participate in a self-swabbing scheme for a longer period. All swabs contained c-myc-DNA. In 119 swabs, we identified any of 14 viruses but no bacteria. The positivity rate of influenza was similar to that in the German physician sentinel.</p></div><div type="abstract" xml:lang="en"><p><b>CONCLUSION</b></p><p>Self-collection of anterior nasal swabs proofed to be feasible, was well accepted by participants, gave valid results and was an informative adjunct to syndromic data.</p></div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">30925029</PMID><DateCompleted><Year>2020</Year><Month>01</Month><Day>27</Day></DateCompleted><DateRevised><Year>2020</Year><Month>04</Month><Day>21</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1750-2659</ISSN><JournalIssue CitedMedium="Internet"><Volume>13</Volume><Issue>4</Issue><PubDate><Year>2019</Year><Month>07</Month></PubDate></JournalIssue><Title>Influenza and other respiratory viruses</Title><ISOAbbreviation>Influenza Other Respir Viruses</ISOAbbreviation></Journal><ArticleTitle>Feasibility study for the use of self-collected nasal swabs to identify pathogens among participants of a population-based surveillance system for acute respiratory infections (GrippeWeb-Plus)-Germany, 2016.</ArticleTitle><Pagination><MedlinePgn>319-330</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1111/irv.12644</ELocationID><Abstract><AbstractText Label="BACKGROUND">Internet-based participatory surveillance systems, such as the German GrippeWeb, monitor the frequency of acute respiratory illnesses on population level. In order to interpret syndromic information better, we devised a microbiological feasibility study (GrippeWeb-Plus) to test whether self-collection of anterior nasal swabs is operationally possible, acceptable for participants and can yield valid data.</AbstractText><AbstractText Label="METHODS">We recruited 103 GrippeWeb participants (73 adults and 30 children) and provided them with a kit, instructions and a questionnaire for each sample. In the first half of 2016, participants took an anterior nasal swab and sent it to the Robert Koch Institute whenever an acute respiratory illness occurred. Reporting of illnesses through the GrippeWeb platform continued as usual. We analysed swabs for the presence of human c-myc-DNA and 22 viral and bacterial pathogens. After the study, we sent participants an evaluation questionnaire. We analysed timeliness, completeness, acceptability and validity.</AbstractText><AbstractText Label="RESULTS">One hundred and two participants submitted 225 analysable swabs. Ninety per cent of swabs were taken within 3 days of symptom onset. Eighty-nine per cent of swabs had a corresponding reported illness in the GrippeWeb system. Ninety-nine per cent of adults and 96% of children would be willing to participate in a self-swabbing scheme for a longer period. All swabs contained c-myc-DNA. In 119 swabs, we identified any of 14 viruses but no bacteria. The positivity rate of influenza was similar to that in the German physician sentinel.</AbstractText><AbstractText Label="CONCLUSION">Self-collection of anterior nasal swabs proofed to be feasible, was well accepted by participants, gave valid results and was an informative adjunct to syndromic data.</AbstractText><CopyrightInformation>© 2019 The Authors. Influenza and Other Respiratory Viruses Published by John Wiley & Sons Ltd.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Haussig</LastName><ForeName>Joana M</ForeName><Initials>JM</Initials><Identifier Source="ORCID">0000-0002-5216-3472</Identifier><AffiliationInfo><Affiliation>Department of Infectious Disease Epidemiology, Robert Koch Institute, Berlin, Germany.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Postgraduate Training for Applied Epidemiology (PAE), Robert Koch Institute, Berlin, Germany.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>European Centre for Disease Prevention and Control (ECDC), Stockholm, Sweden.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Targosz</LastName><ForeName>Angelina</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Centre for Biological Threats and Special Pathogens, Robert Koch Institute, Berlin, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Engelhart</LastName><ForeName>Susanne</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Centre for Biological Threats and Special Pathogens, Robert Koch Institute, Berlin, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Herzhoff</LastName><ForeName>Michael</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Infectious Disease Epidemiology, Robert Koch Institute, Berlin, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Prahm</LastName><ForeName>Kerstin</ForeName><Initials>K</Initials><AffiliationInfo><Affiliation>Department of Infectious Disease Epidemiology, Robert Koch Institute, Berlin, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Buda</LastName><ForeName>Silke</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Department of Infectious Disease Epidemiology, Robert Koch Institute, Berlin, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Nitsche</LastName><ForeName>Andreas</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Centre for Biological Threats and Special Pathogens, Robert Koch Institute, Berlin, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Haas</LastName><ForeName>Walter</ForeName><Initials>W</Initials><AffiliationInfo><Affiliation>Department of Infectious Disease Epidemiology, Robert Koch Institute, Berlin, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Buchholz</LastName><ForeName>Udo</ForeName><Initials>U</Initials><Identifier Source="ORCID">0000-0001-6597-3995</Identifier><AffiliationInfo><Affiliation>Department of Infectious Disease Epidemiology, Robert Koch Institute, Berlin, Germany.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal 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Studies</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005858" MajorTopicYN="N" Type="Geographic">Germany</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D007251" MajorTopicYN="N">Influenza, Human</DescriptorName><QualifierName UI="Q000175" MajorTopicYN="N">diagnosis</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D009666" MajorTopicYN="N">Nose</DescriptorName><QualifierName UI="Q000821" MajorTopicYN="Y">virology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D012141" MajorTopicYN="N">Respiratory Tract Infections</DescriptorName><QualifierName UI="Q000175" MajorTopicYN="Y">diagnosis</QualifierName><QualifierName UI="Q000821" MajorTopicYN="Y">virology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D013048" MajorTopicYN="N">Specimen Handling</DescriptorName><QualifierName UI="Q000379" MajorTopicYN="Y">methods</QualifierName><QualifierName UI="Q000592" MajorTopicYN="N">standards</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D011795" MajorTopicYN="N">Surveys and Questionnaires</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D014780" MajorTopicYN="N">Viruses</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName><QualifierName UI="Q000302" MajorTopicYN="Y">isolation & purification</QualifierName></MeshHeading></MeshHeadingList><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="Y">epidemiological monitoring</Keyword><Keyword MajorTopicYN="Y">human</Keyword><Keyword MajorTopicYN="Y">influenza</Keyword><Keyword MajorTopicYN="Y">patient generated health data</Keyword><Keyword MajorTopicYN="Y">public health surveillance</Keyword><Keyword MajorTopicYN="Y">respiratory tract infections</Keyword><Keyword MajorTopicYN="Y">self-swabbing</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2018</Year><Month>12</Month><Day>06</Day></PubMedPubDate><PubMedPubDate PubStatus="revised"><Year>2019</Year><Month>02</Month><Day>20</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2019</Year><Month>02</Month><Day>21</Day></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2019</Year><Month>3</Month><Day>30</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2020</Year><Month>1</Month><Day>28</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2019</Year><Month>3</Month><Day>30</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">30925029</ArticleId><ArticleId IdType="doi">10.1111/irv.12644</ArticleId><ArticleId IdType="pmc">PMC6586186</ArticleId></ArticleIdList><ReferenceList><Reference><Citation>Euro Surveill. 2007 Jul 01;12(7):E5-6</Citation><ArticleIdList><ArticleId IdType="pubmed">17991409</ArticleId></ArticleIdList></Reference><Reference><Citation>Am J Epidemiol. 2010 Jun 1;171(11):1157-64</Citation><ArticleIdList><ArticleId IdType="pubmed">20439308</ArticleId></ArticleIdList></Reference><Reference><Citation>Am J Public Health. 2015 Oct;105(10):2124-30</Citation><ArticleIdList><ArticleId IdType="pubmed">26270299</ArticleId></ArticleIdList></Reference><Reference><Citation>Euro Surveill. 2015 Mar 19;20(11):</Citation><ArticleIdList><ArticleId IdType="pubmed">25811646</ArticleId></ArticleIdList></Reference><Reference><Citation>J Virol Methods. 2009 Mar;156(1-2):102-6</Citation><ArticleIdList><ArticleId IdType="pubmed">19041346</ArticleId></ArticleIdList></Reference><Reference><Citation>Commun Dis Intell Q Rep. 2009 Sep;33(3):316-22</Citation><ArticleIdList><ArticleId IdType="pubmed">20043602</ArticleId></ArticleIdList></Reference><Reference><Citation>Euro Surveill. 2015 Mar 12;20(10):21058</Citation><ArticleIdList><ArticleId IdType="pubmed">25788252</ArticleId></ArticleIdList></Reference><Reference><Citation>J Med Internet Res. 2018 Mar 01;20(3):e71</Citation><ArticleIdList><ArticleId IdType="pubmed">29496658</ArticleId></ArticleIdList></Reference><Reference><Citation>BMC Public Health. 2006 Oct 04;6:242</Citation><ArticleIdList><ArticleId IdType="pubmed">17018161</ArticleId></ArticleIdList></Reference><Reference><Citation>PLoS One. 2011;6(6):e21335</Citation><ArticleIdList><ArticleId IdType="pubmed">21731708</ArticleId></ArticleIdList></Reference><Reference><Citation>Euro Surveill. 2014 Jan 30;19(4):</Citation><ArticleIdList><ArticleId IdType="pubmed">24507468</ArticleId></ArticleIdList></Reference><Reference><Citation>J Clin Microbiol. 1999 Dec;37(12):3971-4</Citation><ArticleIdList><ArticleId IdType="pubmed">10565916</ArticleId></ArticleIdList></Reference><Reference><Citation>PLoS Curr. 2015 May 27;7:</Citation><ArticleIdList><ArticleId IdType="pubmed">26075141</ArticleId></ArticleIdList></Reference><Reference><Citation>Clin Microbiol Infect. 2014 Jan;20(1):17-21</Citation><ArticleIdList><ArticleId IdType="pubmed">24350723</ArticleId></ArticleIdList></Reference><Reference><Citation>PLoS One. 2012;7(11):e48508</Citation><ArticleIdList><ArticleId IdType="pubmed">23155387</ArticleId></ArticleIdList></Reference></ReferenceList></PubmedData></pubmed><affiliations><list><country><li>Allemagne</li><li>Suède</li></country><region><li>Berlin</li><li>Svealand</li></region><settlement><li>Berlin</li><li>Stockholm</li></settlement></list><tree><country name="Allemagne"><region name="Berlin"><name sortKey="Haussig, Joana M" sort="Haussig, Joana M" uniqKey="Haussig J" first="Joana M" last="Haussig">Joana M. Haussig</name></region><name sortKey="Buchholz, Udo" sort="Buchholz, Udo" uniqKey="Buchholz U" first="Udo" last="Buchholz">Udo Buchholz</name><name sortKey="Buda, Silke" sort="Buda, Silke" uniqKey="Buda S" first="Silke" last="Buda">Silke Buda</name><name sortKey="Engelhart, Susanne" sort="Engelhart, Susanne" uniqKey="Engelhart S" first="Susanne" last="Engelhart">Susanne Engelhart</name><name sortKey="Haas, Walter" sort="Haas, Walter" uniqKey="Haas W" first="Walter" last="Haas">Walter Haas</name><name sortKey="Haussig, Joana M" sort="Haussig, Joana M" uniqKey="Haussig J" first="Joana M" last="Haussig">Joana M. Haussig</name><name sortKey="Herzhoff, Michael" sort="Herzhoff, Michael" uniqKey="Herzhoff M" first="Michael" last="Herzhoff">Michael Herzhoff</name><name sortKey="Nitsche, Andreas" sort="Nitsche, Andreas" uniqKey="Nitsche A" first="Andreas" last="Nitsche">Andreas Nitsche</name><name sortKey="Prahm, Kerstin" sort="Prahm, Kerstin" uniqKey="Prahm K" first="Kerstin" last="Prahm">Kerstin Prahm</name><name sortKey="Targosz, Angelina" sort="Targosz, Angelina" uniqKey="Targosz A" first="Angelina" last="Targosz">Angelina Targosz</name></country><country name="Suède"><region name="Svealand"><name sortKey="Haussig, Joana M" sort="Haussig, Joana M" uniqKey="Haussig J" first="Joana M" last="Haussig">Joana M. Haussig</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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